Coagulation and Mental Disorders

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Coagulation and Mental Disorders

The neurovascular unit is a key player in brain development, homeostasis, and pathology. Mental stress affects coagulation, while severe mental illnesses, such as recurrent depression and schizophrenia, are associated with an increased thrombotic risk and cardiovascular morbidity. Evidence indicates that the hemostatic system is involved to some extent in the pathogenesis, morbidity, and progno...

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Disseminated intravascular coagulation and coagulation disorders.

PURPOSE OF REVIEW An update on recent developments in diagnosis and treatment of disseminated intravascular coagulation. RECENT FINDINGS Disseminated intravascular coagulation is defined as a typical disease condition with laboratory findings indicating massive coagulation activation and reduction in procoagulant capacity. Clinical syndromes associated with the condition are consumption coagu...

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Coagulation disorders.

The risk of severe haemorrhage in pregnancy is well recognized, and uncontrolled bleeding remains a major cause of maternal death throughout the world, including the British Isles. The haemochorial system of human placentation carries with it an inherent risk of haemorrhage and this probably explains why the serious congenital disorders of haemostasis are predominantly found in the male. In pre...

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Postoperative bleeding and coagulation disorders.

PURPOSE OF REVIEW New data have been made available in the field of haemostasis and thrombosis. Some long-awaited answers to important questions have been published, and some debates have benefited from an updated perspective. RECENT FINDINGS Two important domains are addressed in this update: massive bleeding (1/1/1 ratios and fibrinogen concentrates) and the management of direct oral antico...

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Transfusion Medicine and Coagulation Disorders

Coagulation and bleeding assume particular importance when operations are performed on the heart using extracorporeal circulation. This chapter begins with a discussion of the depth and breadth of hemostasis relating to cardiac procedures, beginning with coagulation pathophysiology. The pharmacology of heparin and protamine is described next. This background is then applied to treatment of the ...

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ژورنال

عنوان ژورنال: Rambam Maimonides Medical Journal

سال: 2014

ISSN: 2076-9172

DOI: 10.5041/rmmj.10170